Abstract: The selection of empirical parameters for bedrock end resistance and side resistance significantly impacts pile foundation design. Optimizing these parameter values can effectively reduce both the investment cost and construction timeline of pile foundation projects. Based on analyses grounded in Hubei Provincial local standards and relevant industry standards, the relationship between the theoretical calculated values of single pile bearing capacity and empirical parameter selections was statistically examined under several working conditions. The results indicated that the lower limit value of empirical parameters specified in the Hubei Provincial reduction standards only when all the following conditions are simultaneously met, such as a slenderness ratio equal 0, slightly weathered bedrock, highly fractured bedrock, and bedrock classified as extremely soft rock. When utilizing rock-socketed piles, the disparity between empirical parameters and theoretical calculated values increases progressively with rising rock-socketed ratio, and pile foundation design must comprehensively consider both the rock-socketed depth and the rock strength. In granite regions, the pile bearing stratum should be set within non-fractured moderately or slightly weathered strata, utilizing empirical parameter values within the overlapping interval of standard empirical parameters. The research results can provide a reference for selecting design parameters for bedrock layer pile foundations within Hubei Province.