Abstract: The inter-slice force assumption in the traditional limit equilibrium method lacks a mechanical basis under slope seepage conditions. We used a seepage stability analysis method based on shear deformation compatibility, taken the deformation characteristics of materials as one of the factors considered in the inter-slice force assumption. Firstly, by fully analyzing the inter-slice shear force and the deformation movement trend of slices, an inter-slice force assumption considering deformation compatibility was proposed. Secondly, under the consideration of seepage conditions, through theoretical analysis, the solution formulas for the inter-slice force and the bottom force of the limit equilibrium method based on shear deformation compatibility were further derived, and the solution method for the safety factor was given. The proposed method was verified by taking the ACADS test question as an example. The results showed that the calculation results of the proposed method were close to those of the Morgenstern-Price method, which proved the reliability of the limit equilibrium method based on shear deformation compatibility.